Pricing
One protein or twenty — the second one costs a fraction of the first.
Most of what you pay for is standing the project up, not running each culture. Order a panel and the per-protein price falls to about €600, everything included.
€2,400
One protein, 1 L E. coli, all in
€600
Per protein at 20 in one batch
−75%
Saving on a batch of 20
Free
Quote, and advice on which route to use
Batch pricing · 1 L E. coli
Work out your number.
Gene synthesis, the culture, purification, QC and EU shipping — all of it, per protein. Drag the slider or pick a preset.
€600
per protein
€11,995
batch total
−75%
vs. ordering singly
| Proteins in one batch | Per protein | Batch total | Saving |
|---|---|---|---|
| 1 | €2,400 | €2,400 | — |
| 5 | €884 | €4,420 | −63% |
| 10 | €695 | €6,945 | −71% |
| 20 | €600 | €11,995 | −75% |
| 50 | €543 | €27,145 | −77% |
Above 50 proteins, talk to us. At that point the constraint stops being price and starts being how we schedule the work, and a published number would be misleading.
Why this matters
Screening a panel should not cost twenty times one protein.
If you are designing binders computationally, one protein rarely answers anything. You need the variant series — the point is the comparison between them, not any single member of it.
Pricing that charges full freight for each construct quietly pushes you into testing three designs when you should be testing twenty, and you end up picking a winner from a field too small to contain one.
A worked example
€11,995
20 designed variants, each expressed in a 1 L E. coli culture, purified, QC'd and shipped — €600 per protein.
Ordering the same twenty one at a time would cost €48,000.
Everything else
Services priced individually
Mammalian work, analytics and larger bacterial scale are not part of the batch model above.
Mammalian expression
Transient CHO, 100 mL Small-scale mammalian, for when you need to know whether it works at all. | from €3,200 |
Transient CHO, 1 L Standard mammalian production run. 31 working days. | from €5,900 |
Recombinant IgG, 1 L Antibody project including Protein A capture and non-reduced purity check. | from €4,200 |
Analytics
BLI affinity One interaction pair. Rates, affinity constant and raw sensorgrams. 5 working days standalone. | from €1,200 |
Western blot One target, sample and control lanes, blot image supplied. | from €480 |
Larger bacterial scale
E. coli, up to 10 L Once a 1 L run has shown the protein behaves and you need more material. | from €6,900 |
Prices exclude VAT and assume delivery within the EU. Gene synthesis is included in every production package rather than billed separately.
What moves the number
Four things, in roughly this order.
How many proteins at once
By far the biggest lever, and the reason the table above exists. Setting a project up costs roughly the same whether it carries one construct or twenty.
How hard the target is
A well-behaved soluble domain and a membrane-associated protein with four disulfides are not the same job, and we will not pretend they are.
Which system it needs
Mammalian expression costs more than bacterial and takes about ten working days longer. If E. coli will do, we will tell you.
Whether you bring a construct
A validated plasmid removes synthesis and cloning, and takes both time and cost out of the quote.
Questions
About how we price
Is €600 per protein real, or a headline?
Real, at 20 proteins produced in one batch — and it covers everything: gene synthesis, the 1 L culture, purification, QC and shipping. The batch total at that quantity is €11,995. Use the calculator for any other number; it is the same arithmetic we quote from.
Why is one protein so much more expensive per unit?
Because most of the cost is standing the project up rather than running each culture: the strain work, the method, the columns, the analytics setup and the paperwork happen once whether you order one construct or twenty. We could average that across everyone and charge a flat mid-price, but then panel customers would be subsidising single orders.
Do the proteins in a batch have to be related?
No, though it helps if they suit the same expression route. Twenty variants of one designed binder is the typical case and the easiest to run. Twenty unrelated targets is fine too — tell us what they are and we will say whether they can genuinely share a batch.
What if some of them fail?
In a panel some constructs almost always express better than others — that is usually the point of running a panel. We agree in writing before starting how partial success is handled, so it is settled while nobody is under pressure.
Does batch pricing apply to CHO as well?
The same principle applies, but mammalian panels are quoted individually rather than from a published table. Tell us how many constructs you have and we will price it.
Are these prices or estimates?
The quote you receive is a fixed price for your specific project, and it does not move afterwards unless you change the brief.
What is not included?
Shipping outside the EU, tag cleavage, and refolding from inclusion bodies where that becomes necessary. Gene synthesis, purification, standard QC — including the endotoxin measurement on bacterial batches — and EU shipping are all in the price.
Is there a minimum order or a subscription?
Neither. One protein is a perfectly normal order and we do not ask for a commitment beyond it.
Do you offer academic pricing?
Yes. Tell us you are an academic group when you request the quote.
How do I actually pay?
Invoice in EUR against a purchase order, on terms agreed at the quote stage. We are used to institutional procurement and will complete supplier forms.
How many are you making?
Send the sequences and we will price the batch. One protein or 20 — the quote comes back the same way, usually within a working day.